Identification of alternative splicing events regulated by the splicing factor SRSF1 using data from exon-junction microarray technologies

Analysis to identify genome-wide differential alternative splicing events in A549 cells in which the levels of the gene SRSF1 were down-regulated with a specific siRNA 9 samples from three independent experiments using A549 cells transfected with lipofectamine alone, scramble siRNA or SRSF1 siRNA

本分析旨在鉴定经特异性小干扰RNA（siRNA）下调SRSF1基因表达的A549细胞中的全基因组差异可变剪接事件。该分析所用样本共9份，取自3次独立重复实验，所用细胞分别为仅转染脂质体转染试剂（Lipofectamine）、转染乱序siRNA（scramble siRNA）或转染SRSF1特异性siRNA的A549细胞。