five

This file contains data used in Fig 7.

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The first sheet contains the distribution of exit times prior to spindle alignment in 2 SPoC mutants (bub2Δ and kin4Δ) calculated from MaBoSS simulations of Model 6. The second sheet contains example trajectories of the simulated spindle angle in kar9Δ dyn1-AID osTIR1 cells, modelled as a Brownian motion. The third sheet contains the distribution of alignment times in kar9Δ dyn1-AID osTIR1 cells calculated from Brownian motion simulations. The fourth sheet contains the distribution of the difference between the spindle alignment and exit times for a bub2Δ mutant prior to spindle alignment, calculated from MaBoSS simulation of model 6 and Brownian motion simulations of spindle alignment. The fifth sheet contains the predicted percentage of binucleate cell phenotype after 1 cell division, calculated from MaBoSS simulation of Model 6 and Brownian motion simulations of spindle alignment, for various mutants. (XLSX)
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2020-11-12
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