This file contains data used in Fig 7.

The first sheet contains the distribution of exit times prior to spindle alignment in 2 SPoC mutants (bub2Δ and kin4Δ) calculated from MaBoSS simulations of Model 6. The second sheet contains example trajectories of the simulated spindle angle in kar9Δ dyn1-AID osTIR1 cells, modelled as a Brownian motion. The third sheet contains the distribution of alignment times in kar9Δ dyn1-AID osTIR1 cells calculated from Brownian motion simulations. The fourth sheet contains the distribution of the difference between the spindle alignment and exit times for a bub2Δ mutant prior to spindle alignment, calculated from MaBoSS simulation of model 6 and Brownian motion simulations of spindle alignment. The fifth sheet contains the predicted percentage of binucleate cell phenotype after 1 cell division, calculated from MaBoSS simulation of Model 6 and Brownian motion simulations of spindle alignment, for various mutants. (XLSX)第一个工作表包含基于模型6（Model 6）的MaBoSS模拟计算得到的2种SPoC突变体（bub2Δ与kin4Δ）在纺锤体列队（spindle alignment）前的退出时间分布。 第二个工作表包含kar9Δ dyn1-AID osTIR1细胞中模拟纺锤体角度的示例轨迹，该轨迹以布朗运动（Brownian motion）为模型。 第三个工作表包含基于布朗运动模拟计算得到的kar9Δ dyn1-AID osTIR1细胞的纺锤体列队时间分布。 第四个工作表包含基于模型6的MaBoSS模拟与纺锤体列队的布朗运动模拟计算得到的、bub2Δ突变体在纺锤体列队前的纺锤体列队时间与退出时间的差值分布。 第五个工作表包含针对多种突变体、基于模型6的MaBoSS模拟与纺锤体列队的布朗运动模拟计算得到的1次细胞分裂后双核细胞表型的预测占比。(XLSX)