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Data on studied markers for the VDR gene.

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https://figshare.com/articles/dataset/_Data_on_studied_markers_for_the_VDR_gene_/706109
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Note: Genotypes were expressed in RFLP nomenclature: uppercase letters denote the absence of a restriction site, while lowercase letters indicate the presence of a restriction site. In other words, VDR genotypes of each subject were identified according to the digestion pattern, and alleles were identified according to the presence (f or b) or absence (F or B) of the FokI and BsmI sites, respectively. The F and B alleles correspond to the C and A nucleotides, respectively. Abbreviations: VDR, vitamin D receptor; SNPs, single nucleotide polymorphisms; PCR, polymerase chain reaction; RFLP, restriction fragment length polymorphism.

注:基因型采用限制性片段长度多态性(Restriction Fragment Length Polymorphism, RFLP)命名规则:大写字母代表限制性酶切位点缺失,小写字母代表限制性酶切位点存在。换言之,所有受试者的维生素D受体(Vitamin D Receptor, VDR)基因型均依据酶切图谱进行鉴定,等位基因则分别依据FokI和BsmI酶切位点的存在与缺失进行判定:FokI位点存在对应f、缺失对应F;BsmI位点存在对应b、缺失对应B。其中F等位基因对应C核苷酸,B等位基因对应A核苷酸。 缩写说明:VDR:维生素D受体;SNPs(Single Nucleotide Polymorphisms):单核苷酸多态性;PCR(Polymerase Chain Reaction):聚合酶链式反应;RFLP:限制性片段长度多态性。
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2013-05-22
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