Transcriptional profile of peripheral blood mononuclear cells PBMC from type 1 Diabetes Mellitus Patients

ChEBI2012-08-24 更新2026-07-21 收录

自身免疫疾病转录组

糖尿病免疫机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MEXP-3348 数据链接链接失效反馈

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Transcriptional profile of peripheral blood mononuclear cells PBMC from type 1 Diabetes Mellitus Patients

创建时间：

2012-08-24

Beta cell-specific CD8+ T cells maintain stem-cell memory-associated epigenetic programs during type 1 diabetes (scATAC-seq). Beta cell-specific CD8+ T cells maintain stem-cell memory-associated epigenetic programs during type 1 diabetes (scATAC-seq)

自身免疫T细胞表观遗传学

糖尿病免疫机制

The pool of beta cell-specific CD8+ T-cells in type 1 diabetes (T1D) sustains an autoreactive potential despite having access to a constant source of antigen. To investigate the long-lived nature of t

NIAID Data Ecosystem20

miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes

糖尿病免疫机制

Treg细胞调控

In type 1 diabetes (T1D), the appearance of multiple islet autoantibodies indicates the onset of islet autoimmunity, often many years before clinical symptoms arise. However, the underlying molecular

NIAID Data Ecosystem20

Top nodes in ET1DRE high confidence transcriptional intersection analysis

糖尿病免疫机制

信号网络分析

This network shows the top ranked ET1DRE signaling pathway nodes, which are predicted to regulate genes that are preferentially repressed in circulating immune cells from individuals with type 1 diabe

NIAID Data Ecosystem10

Single-cell transcriptomics implicate the alteration of peripheral immune cells and interaction with renal macrophages driven by T2DM

单细胞转录组学

糖尿病免疫机制

The alternation of peripheral immune cells in diabetes is complicated. We performed scRNA-seq on db/db mice to explore the cellular changes in T2DM. peripheral immune cells of db/db or wt mice were

NIAID Data Ecosystem20

Non-Juvenile Sjogren Syndrome (non-SjS) samples for Juvenile Sjogrens Syndrome (JSS) Transcriptome Study

自身免疫疾病转录组

单核细胞炎症特征分析

To investigate the inflammatory signature and transcriptomical changes in CD14 positive monocytes, we have isolated and purified monocytes cells from whole blood. Bulk RNA-seq were conducted with an I

NIAID Data Ecosystem10

Transcriptional profile of peripheral blood mononuclear cells PBMC from type 1 Diabetes Mellitus Patients

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