Genome-wide maps of H3K27ac and H2A.Zac in HeLa K cells after depletion of PWWP2A by siRNA-mediated knockdown.. Genome-wide maps of H3K27ac and H2A.Zac in HeLa K cells after depletion of PWWP2A by siRNA-mediated knockdown.

Our study investigates changes in acetylation levels on H3K27 and H2A.Z after PWWP2A depletion as measured by ChIP-seq. Overall design: In this study we examined two different histone modifications in HeLa K cells after siRNA-mediated depletion of PWWP2A as measured by ChIP-seq.

本研究通过染色质免疫共沉淀测序（ChIP-seq）技术，探究了PWWP2A基因敲低后H3K27与H2A.Z的乙酰化水平变化。总体实验设计：本研究采用小干扰RNA（siRNA）介导的PWWP2A基因敲低体系，通过染色质免疫共沉淀测序（ChIP-seq）技术，对HeLa K细胞中的两种不同组蛋白修饰进行了检测分析。