HIV-1 neutralizing antibody D5_AR bound to HIV-1 gp41 coiled-coil pocket IQN17

HIV-1 neutralizing antibody D5_AR bound to HIV-1 gp41 coiled-coil pocket IQN17 Descriptor: Neutralizing antibody D5_AR Heavy Chain, Neutralizing antibody D5_AR Light Chain, Transmembrane protein gp41 IQN17 peptide Authors: Filsinger Interrante, M.V, Tang, S, Fernandez, D, Kim, P.S. Deposit date: 2024-02-01 Release date: 2025-07-02 Last modified: 2025-07-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Utilizing Machine Learning to Improve Neutralization Potency of an HIV-1 Antibody Targeting the gp41 N-Heptad Repeat. Acs Chem.Biol., 20, 2025HIV-1中和抗体 (neutralizing antibody) D5_AR结合于HIV-1 gp41卷曲螺旋口袋 (coiled-coil pocket) IQN17 描述符：中和抗体D5_AR重链、中和抗体D5_AR轻链、跨膜蛋白 (transmembrane protein) gp41 IQN17肽段 (peptide) 作者：Filsinger Interrante, M.V.、Tang, S.、Fernandez, D.、Kim, P.S. 提交日期：2024-02-01 发布日期：2025-07-02 最后修改日期：2025-07-30 实验方法：X射线衍射 (X-RAY DIFFRACTION)，分辨率2.2埃 (Å) 引用文献：《利用机器学习提升靶向gp41 N端七肽重复区的HIV-1抗体中和效力》，发表于ACS Chem. Biol., 第20卷，2025年