Heyndrickxia coagulans JF1 trains with Potent Ethanol-Degrading Capacity: In Vitro Screening and Functional Characterization

we selected H. coagulans JF1, which exhibits the strongest ethanol-degrading ability, for whole-genome sequencing to obtain its functional information. Strain JF1 was selected for whole-genome sequencing, revealing a circular chromosome of 3,657,992 bp with a GC content of 46.22% . The genome contains 3,673 genes, including 3,469 protein-coding sequences (CDS) and 77 tRNA genes. Functional annotation via COG and KEGG databases showed enrichment in pathways related to amino acid/carbohydrate metabolism, energy production, and membrane transport. Notably, genes encoding ADH (adh) and ALDH (adhE) were identified, providing genetic evidence for its ethanol-degrading potential .

我们选取了乙醇降解能力最强的凝结芽孢杆菌（H. coagulans）JF1进行全基因组测序，以获取其功能相关信息。针对JF1菌株的全基因组测序结果显示，其基因组为长度3657992 bp的环状染色体，GC含量为46.22%。该基因组共包含3673个基因，其中包括3469个蛋白质编码序列（CDS）与77个转运RNA（tRNA）基因。通过COG数据库与KEGG数据库开展功能注释分析，结果显示其基因组显著富集于氨基酸/碳水化合物代谢、能量产生以及膜转运相关通路。值得注意的是，本研究鉴定到了编码乙醇脱氢酶（ADH，adh）与乙醛脱氢酶（ALDH，adhE）的基因，为该菌株具备乙醇降解潜力提供了遗传学证据。