Malmö Preventive Project

The MPP was started in the early 70's as a screening survey in the middle-aged population of Malmö, the third largest city of Sweden. Subjects born in Malmö and residents of the city were invited for a clinical examination, questionnaire and blood sampling. In all 22,444 men and 10,902 women participated during the period 1974-1992. During a later follow-up, the MPP-Re-examination (MPP-RES) in all 17,284 of the original screenes attended in 2002-2006. Purpose: 1. To screen for cardiovascular risk-factors and alcohol abuse in the local population, and to offer intervention to subjects at risk; 2. To use DNA (at MPP-RES) for analyses of genetic risks of type-2 diabetes and cardiovascular disease, as well as some cancers.马尔默预防项目（Malmö Preventive Project，MPP）于20世纪70年代初启动，最初是针对瑞典第三大城市马尔默的中年人群开展的筛查调查。项目邀请在马尔默出生且常住该市的受试者接受临床检查、问卷调查及血液样本采集。1974年至1992年间，总计共有22444名男性与10902名女性参与了该项目。在后续随访阶段，项目组于2002年至2006年间开展了MPP复查项目（MPP-Re-examination，MPP-RES），共有17284名最初参与筛查的受试者参与了此次复查。 研究目的： 1. 针对本地人群筛查心血管疾病危险因素与酒精滥用情况，并为存在风险的受试者提供干预措施； 2. 在MPP复查项目（MPP-RES）中利用DNA样本，分析2型糖尿病、心血管疾病及部分癌症的遗传风险。