Immune Development in Pediatric Transplantation (CTOTC-02)

This is a multi-center, prospective, observational cohort study in pediatric renal transplant recipients. Target accrual in this study is 75 subjects over 2 years. Enrolled subjects will be categorized based on pre-enrollment CMV and EBV serology testing and be placed in the viral positive group, viral negative group, or split serology group. Subjects in the split serology group will not count towards study accrual target but will be included in analyses. CMV and EBV serology tests obtained for transplant evaluation will be collected retrospectively and used to categorize subjects. Subjects with previously negative serologies but later have positive serology results as indicated by testing on day of transplantation will be placed into the viral positive group. Subjects will have 6 study visits over 12 months as participants in this study.