The relationship between type-specific oral HPV infections detected at two-week and six-month sampling intervals.

The flow chart shows the relationship between oral HPV infections detected at a six-month sampling interval (visits 1 and 14, above the horizontal line) and categorized as persistent (+/+), cleared (+/−), newly detected (−/+), or absent (−/−) and their categorization as persistent (P), transient (T), or absent (A) infections under the two-week interval definitions (see methods). Persistent infections under the two-week categorization that subsequently cleared (C) are also indicated. However, cleared infections which recurred are not included in the figure, refer to text. A summary of infections as categorized under a two-week sampling interval as persistent, transient, absent (A) and cleared is included below the horizontal line. A total of 3365 possible infections were evaluated at visits 1 and 14 ((91×37) −2).

本流程图展示了横轴线上方、以6个月为采样间隔（即第1次和第14次随访）检测得到的口腔人乳头瘤病毒（Human Papillomavirus, HPV）感染的关联情况，此类感染被分为持续性（+/+）、已清除（+/−）、新检出（−/+）以及未感染（−/−）四类；同时还展示了基于2周间隔定义（详见方法部分）的感染分类结果，即持续性（P）、一过性（T）与未感染（A）三类。本图同时标注了在2周间隔分类体系下原本属于持续性、后续发生清除的感染（标记为C）。不过，曾被清除后又复发的感染并未纳入本图，具体细节可参见正文说明。横轴线下方汇总了以2周为采样间隔分类的感染情况，涵盖持续性、一过性、未感染（A）以及已清除四类。在第1次和第14次随访中，共对3365例潜在感染进行了评估（计算公式为(91×37) −2）。