Obese individuals show gene expression changes over time after influenza vaccination

Analysis of systemic gene expression to comprehend the immune response following vaccination. Blood samples were collected from participants days and weeks post Fluzone vaccination. Gene expression profiles were compared between high and low responders in both obese and non-obese groups.

本研究通过系统性基因表达分析，旨在阐明疫苗接种后的免疫应答反应。研究人员采集了受试者在接种Fluzone疫苗后数日至数周的血液样本，并在肥胖组与非肥胖组中分别对比高应答者与低应答者的基因表达谱。