EZH2 inhibtion and IFNy treatment of patient derived organoids [RNA-seq]. EZH2 inhibtion and IFNy treatment of patient derived organoids [RNA-seq]

We report the transcriptomics of squamous lung cancer patient derived tumoroids treated with EZH2 inhibitor and IFNy Overall design: To determine that EZH2 inhibition and IFNy upregulate genes involved in antigen presentation machinery and immunogenicity

本研究报道了经EZH2抑制剂(EZH2 inhibitor)与干扰素γ(IFNy)处理的肺鳞状细胞癌患者来源肿瘤类器官的转录组学数据。实验设计概述：本研究旨在验证EZH2抑制与干扰素γ处理可上调参与抗原呈递机制及免疫原性的相关基因。