Mus musculus strain:686 Raw sequence reads. Mus musculus strain:686

The goal of this project is to undersnand the mechanism of how arsenic act as a potent co-mutagen of ultraviolet light that amplifies UVR mutagenesis and that generates a unique mutational signature commonly found in human cancers of the skin.

本项目旨在阐明砷作为紫外线（Ultraviolet Light，UVR）的强效协同诱变剂的作用机制：该物质可放大紫外线辐射的诱变效应，并产生一种常见于人类皮肤恶性肿瘤的独特突变特征（Mutational Signature）。