RNA transcriptome data from C57BL/6 tissue resident peritoneal macrophages over expressing microRNA 708 or control. RNA transcriptome data from C57BL/6 tissue resident peritoneal macrophages over expressing microRNA 708 or control

RNA transcriptome data from C57BL/6 tissue resident peritoneal macrophages over expressing microRNA 708 or control. The role of microRNA-708 in shaping macrophage biology remains mostly unknown. Here, using lentiviral vectors we overexpressed microRNA-708 in vivo in C57BL/6 mice peritoneal macrophages and investigated mRNA changes in these cells after 4 days.

本数据集源自过表达微小RNA-708（microRNA 708）或转染对照的C57BL/6小鼠组织驻留腹膜巨噬细胞的RNA转录组（RNA transcriptome）数据。目前，微小RNA-708在调控巨噬细胞生物学功能中的作用仍未得到充分阐明。本研究通过慢病毒载体（lentiviral vectors），在C57BL/6小鼠的腹膜巨噬细胞中实现体内过表达微小RNA-708，并对过表达4天后的这些细胞内的mRNA表达变化展开了分析。