The utility of the early intervention by the multi-disciplinary cooperation in the skin reaction due to EGFR inhibitor: Phase II study

Interventions: We conduct an introduction to the chemotherapy center from diagnosis and treatment department, and, in chemotherapy center, a medical oncologist, a pharmacist or a nurse conducts side effect monitoring using an episode of care sheet (the skin reaction monitoring sheet that we made for the purpose of doing multi-disciplinary cooperation smoothly) at chemotherapy enforcement. By severity of the skin reaction, a tumor physician refers you to a dermatologist, and side effect monitoring, a dermatologist intervene after the next treatment.
Primary outcome(s): Severe skin reaction incidence
Study Design: Single arm Non-randomized

干预措施：本研究从诊疗科室衔接化疗中心，并在化疗中心内，由肿瘤内科医师、药师或护士在化疗实施阶段，使用照护记录单（为顺利推进多学科协作自制的皮肤反应监测表）开展不良反应监测。根据皮肤反应严重程度，肿瘤医师将患者转诊至皮肤科医师，并在后续治疗阶段由皮肤科医师介入开展不良反应监测。
主要结局指标：严重皮肤反应发生率
研究设计：单臂非随机试验