Baseline characteristics of study groups.

BackgroundTo analyse the distribution of spectral domain optical coherence tomography (SD-OCT) biomarkers in different types of vitreomacular adhesion (VMA) associated visual impairment in diabetic macular oedema.MethodsA total of 317 eyes of 202 patients were enrolled. Cases were divided into two groups focal VMA and broad VMA and subjects with no VMA were enrolled as controls. A grading platform was used for evaluating the morphology of diabetic macular oedema (DME), using good-quality SD-OCT images. Grading was done for VMA and the biomarkers. Best corrected visual acuity (BCVA), central retinal thickness (CRT) and central subfield thickness (CSFT) was also recorded.ResultsThe CRT (p = ConclusionThe distribution of OCT biomarkers was similar across all eyes of cases and controls. However, they were more likely to be associated with visual impairment in the presence of VMA than no VMA.背景：本研究旨在分析光谱域光学相干断层扫描（spectral domain optical coherence tomography, SD-OCT）生物标志物在糖尿病黄斑水肿（diabetic macular oedema, DME）合并不同类型玻璃体黄斑粘连（vitreomacular adhesion, VMA）相关视力损害中的分布特征。 方法：本研究共纳入202例患者的317只患眼。将研究对象分为局限性玻璃体黄斑粘连（focal VMA）组与广泛性玻璃体黄斑粘连（broad VMA）组，另纳入无玻璃体黄斑粘连的受试者作为对照。采用高质量SD-OCT图像，通过分级平台评估糖尿病黄斑水肿的形态学特征，并对玻璃体黄斑粘连及相关生物标志物进行分级。同时记录最佳矫正视力（best corrected visual acuity, BCVA）、视网膜中央厚度（central retinal thickness, CRT）及中心亚区厚度（central subfield thickness, CSFT）。 结果：原文此处内容不完整 结论：所有病例组与对照组患眼的OCT生物标志物分布无显著差异，但相较于无玻璃体黄斑粘连的情况，合并玻璃体黄斑粘连时生物标志物更易与视力损害相关联。