Association of positive selection and potential APOBEC3-related mutation.

*Amino acid residues are numbered according to HXB2 Env protein.
**Mutations, GG to AG, GA to AA, GC to AC and GT to AT, at amino acid residues with dN/dS ratio >1 were manually detected.
***GG to AG mutation was sequentially detected 3 times among 10 Env amino acid sequences derived from an individual.

* 氨基酸残基编号参照HXB2包膜蛋白（Env protein）。
** 针对非同义替换与同义替换速率比值（dN/dS ratio）大于1的氨基酸残基，经人工检出如下突变：GG→AG、GA→AA、GC→AC及GT→AT。
*** 在来自单一个体的10条Env蛋白氨基酸序列中，GG→AG突变被连续检出3次。