Anterior abdominal wall ischaemia in association with multiple myeloma

This article reports a case of anterior abdominal wall ischaemia in a 52-year-old woman with an underlying diagnosis of multiple myeloma. The patient underwent emergency surgical debridement of the affected area. The abdominal wall was subsequently resurfaced with a split skin graft. Histological examination of the excised tissue revealed the cause to be a paraneoplastic vasculopathy with immunoglobulin light chain (lambda-type) deposition in the blood vessels of her abdominal apron secondary to multiple myeloma. Literature review has failed to show previous reports of this condition. The differential diagnosis and aetiology are discussed.

本文报告1例52岁女性多发性骨髓瘤（multiple myeloma）患者并发前腹壁缺血（anterior abdominal wall ischaemia）的病例。患者接受了受累区域的急诊手术清创术（emergency surgical debridement），随后采用刃厚皮片移植（split skin graft）修复腹壁创面。对切除组织的组织病理学检查（histological examination）显示，其病因系继发于多发性骨髓瘤的副肿瘤性血管病（paraneoplastic vasculopathy），患者腹部悬垂皮褶的血管内存在免疫球蛋白轻链λ型（lambda-type）沉积。经文献复习，未发现此前有该病症的相关报道。本文并讨论了其鉴别诊断与病因。