Management of nonsteroidal anti-inflammatory drug (NSAID) interactions in students with asthma who visit the surgical department of the Dr. René Puig Bentz dental clinic at the Pedro Henríquez Ureña National University, May-August 2025.

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to control pain,
inflammation, and fever; however, their inappropriate use can trigger adverse
reactions, especially in asthmatic patients, due to NSAID-exacerbated respiratory
disease (NARED or ASA triad). In the dental context, these drugs are often prescribed
postoperatively without always considering the patient's systemic condition. At the Dr.
René Puig Bentz dental clinic, it has been observed that students prescribe NSAIDs
after surgery without comprehensively assessing possible interactions with asthma,
which raises the need to evaluate their level of knowledge and determine whether
their academic training is sufficient.
The study hypothesis establishes that students know how to properly manage NSAID
interactions in asthmatic patients, identify the associated risks, and apply correct
clinical criteria for prescribing them. The null hypothesis maintains that they lack such
knowledge and management skills.
A descriptive, cross-sectional study was conducted in the May-August 2025 semester,
with a sample of 86 students from clinics I to VI. A thirteen-question questionnaire and
a five-item clinical protocol were used to assess theoretical knowledge and practical
decisions. The total population for the period was 150 students.
The results showed that 55.8% had a high level of knowledge, 41.9% had an average
level, and 2.3% had a low level. Clinics II and V obtained the best results, while clinic
VI showed the lowest level, which highlights academic differences between training
levels.
It was concluded that most students have adequate knowledge about the use of
NSAIDs in asthmatic patients, which partially supports the hypothesis. However, the
variability between clinical levels reflects gaps in advanced stages of training. These
findings highlight the importance of reinforcing pharmacological content and
management protocols in patients with asthma to ensure safe and consistent clinical
practice.

非甾体抗炎药（Nonsteroidal Anti-inflammatory Drugs，NSAIDs）被广泛用于缓解疼痛、控制炎症与退热，但不当使用可能引发不良反应，尤其在哮喘患者群体中，这是由于非甾体抗炎药诱发的呼吸系统疾病（NSAID-exacerbated respiratory disease，NARED 又称阿司匹林三联症，ASA triad）。在牙科临床场景中，这类药物常被用于术后镇痛，但医护人员往往未充分考量患者的全身健康状况。在勒内·普伊·本茨（Dr. René Puig Bentz）牙科诊所中，观测到实习医学生在术后开具非甾体抗炎药时，未全面评估其与哮喘病症的潜在相互作用，这凸显出评估学生知识掌握水平、验证其学术培训是否达标的必要性。
本研究的备择假设提出：实习医学生能够正确处理哮喘患者使用非甾体抗炎药的相互作用风险、识别相关不良反应，并遵循恰当的临床处方准则。而虚无假设则认为，学生尚不具备此类知识与临床处置能力。
本研究于2025年5月至8月学期期间开展，采用描述性横断面研究设计，纳入来自1至6号牙科诊所的86名学生作为研究样本。研究通过13项问题的调查问卷与5项临床操作方案，评估受试者的理论知识储备与临床决策能力。本周期内的总研究人群为150名医学生。
研究结果显示，55.8%的学生知识掌握水平为优秀，41.9%为中等，仅2.3%为较差。其中2号与5号诊所的学生表现最优，6号诊所学生的知识水平最低，这一结果凸显了不同培训阶段的学术能力差异。
研究结论表明，多数学生对哮喘患者使用非甾体抗炎药的相关知识掌握充分，这一结果部分支持了备择假设。但不同临床诊所间的能力差异也反映出高阶培训阶段仍存在知识缺口。本研究结果凸显了强化哮喘患者用药相关药理学内容与临床处置规范培训的重要性，以保障临床实践的安全性与一致性。