Cox regression survival models.

Abbreviations: CVD cardiovascular disease.*Covariates: age, sex, study site, participation in the WENBIT study, smoking, family history of coronary heart disease, medical history (hypertension, diabetes, acute myocardial infarction, percutaneous intervention, coronary artery bypass surgery, peripheral vascular disease, cerebrovascular disease, cured cancer, active cancer (not in the cardiovascular mortality analyses due to failure of the model to converge), deep vein thrombosis or vein surgery, pulmonary disease, atrial fibrillation, dyspnea grade 0–4), measured parameters at baseline (body mass index, ECG rhythm, left ventricular ejection fraction, number of coronary vessels with >50% stenosis), laboratory values (estimated glomerular filtration rate, uric acid, hemoglobin, potassium, sodium, C-reactive protein, glycated hemoglobin, low density lipoprotein, troponin T), medication (aspirin, adenosine diphosphate receptor inhibitor, warfarin, angiotensin converting enzyme inhibitor and/or angiotensin receptor blocker, beta-blocker, digoxin, spironolactone, thiazide, calcium antagonist, nitrate, statin, insulin, metformin, sulfonylurea, treatment for chronic obstructive pulmonary disease, non-steroid anti-inflammatory drug, corticosteroid, antidepressant, antipsychotic), and baseline revascularization.Cox regression survival models.

缩写说明：CVD（cardiovascular disease，心血管疾病）。协变量涵盖以下类别：人口统计学特征与研究参与情况（年龄、性别、研究中心、WENBIT研究参与情况、吸烟史）；冠心病相关家族史与既往病史（冠心病家族史，高血压、糖尿病、急性心肌梗死、经皮冠状动脉介入治疗、冠状动脉旁路移植术、外周血管疾病、脑血管疾病、已治愈癌症、活动性癌症（因模型收敛失败未纳入心血管死亡率分析）、深静脉血栓形成或静脉手术史、肺部疾病、心房颤动、呼吸困难分级0-4级）；基线实测生理指标（体质量指数、心电图节律、左心室射血分数、狭窄程度＞50%的冠状动脉血管数量）；实验室检测指标（估算肾小球滤过率、尿酸、血红蛋白、钾离子、钠离子、C反应蛋白、糖化血红蛋白、低密度脂蛋白、肌钙蛋白T）；用药情况（阿司匹林、二磷酸腺苷受体抑制剂、华法林、血管紧张素转换酶抑制剂和/或血管紧张素Ⅱ受体拮抗剂、β受体阻滞剂、地高辛、螺内酯、噻嗪类利尿剂、钙通道阻滞剂、硝酸酯类药物、他汀类药物、胰岛素、二甲双胍、磺脲类药物、慢性阻塞性肺疾病治疗药物、非甾体抗炎药、糖皮质激素、抗抑郁药、抗精神病药）；以及基线血运重建情况。本研究采用Cox比例风险回归生存模型进行分析。