FR901228 in Treating Patients With Previously Treated Unresectable Locally Advanced or Metastatic Colorectal Cancer

RATIONALE: Drugs used in chemotherapy, such as FR901228, work in different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: This phase II trial is studying how well FR901228 works in treating patients with unresectable locally advanced or metastatic colorectal cancer.

治疗原理：诸如FR901228在内的化疗药物，可通过多种不同机制阻止肿瘤细胞分裂，进而抑制其生长或诱导其死亡。
试验目的：本II期临床试验旨在评估FR901228治疗不可切除局部晚期或转移性结直肠癌患者的临床疗效。