Schnitzler Syndrome B Cell Repertoires

Given the presence of autoantibodies and the likelihood of progression of the autoinflammatory disease Schnitzlers Syndrome (SS) to a clonal B cell disorder, Waldenstrom's Macroglobulinaemia (WM), we have analysed the IgH immune repertoire of peripheral B cells.

鉴于自身抗体的存在，且自身炎症性疾病施尼茨勒综合征（Schnitzler Syndrome, SS）可进展为克隆性B细胞疾病华氏巨球蛋白血症（Waldenstrom's Macroglobulinaemia, WM），我们对外周B细胞的免疫球蛋白重链（IgH）免疫组库进行了分析。