A mutant Era GTPase suppresses phenotypes caused by loss of highly conserved YbeY protein in Escherichia coli

In this study, we performed whole-genome sequencing of YbeY deletion strains with improved growth characteristics and have characterized a point mutation in the era gene, era(T99I), that encodes an Era protein variant whose threonine residue at position 99 is replaced by an Isoleucine residue.

本研究对生长特性得到优化的YbeY缺失菌株开展了全基因组测序，并鉴定出era基因中的一处点突变era(T99I)，该突变编码一种Era蛋白变体，其第99位的苏氨酸残基被异亮氨酸残基所取代。