Lenvatinib activates anti-tumor immunity by suppressing immunoinhibitory infiltrates in the tumor microenvironment of advanced hepatocellular carcinoma.zip

This file include datasets generated during analysis and R codes for graphical drawing. The main objective of submitted manuscript is as follows. The mechanism by which the tumor immune microenvironment is edited in human cancer tissues remains to be elucidated. Here, we analyzed the multi-omics of serial tumor and blood samples during lenvatinib monotherapy in 51 patients with advanced hepatocellular carcinoma.

本文件包含分析过程中生成的数据集，以及用于绘图的R代码。本次投稿的论文核心研究目标如下：人类癌组织中肿瘤免疫微环境（tumor immune microenvironment）的重塑机制仍有待阐明。本研究针对51例晚期肝细胞癌患者，分析了仑伐替尼单药治疗期间连续采集的肿瘤及血液样本的多组学（multi-omics）数据。