Unadjusted and adjusted^a geometric means of the HRV indices and percent differences in HRV indices by traffic-related PM₁₀ (TPM₁₀) and by <i>IL6</i>-174G/C genotypes (N = 1549).

HRV indicates heart rate variability: SDNN indicates standard deviation of all NN intervals (units ms); TP, total power (ms2); HF, high frequency power (ms2); LF, low frequency power (ms2). aadjusted for gender, age, age squared, BMI, BMI squared, smoking status, environmental tobacco smoke exposure, alcohol consumption, physical activity, high-sensitivity C-reactive protein, uric acid levels, hypertension, heart disease, diabetes, street and railway noise, seasonal effects and area. bp-values of genotype-specific main effects of the IL6-174G/C polymorphism and TPM10 on HRV (codominant genetic model). cp-values of main effects of the IL6 -174G/C polymorphism on HRV indices were tested for additive, dominant and recessive genetic models; p-values of the most significant mode of inheritance are presented (1additive or 2dominant). dper 1 µg/m3 TPM10 increase. ecompared to reference genotype G/G.心率变异性（heart rate variability, HRV）：SDNN指所有正常窦性心搏间期（NN间期）的标准差（单位：毫秒）；TP为总功率（单位：平方毫秒）；HF为高频功率（单位：平方毫秒）；LF为低频功率（单位：平方毫秒）。 a 本研究校正了性别、年龄、年龄平方、体质量指数（Body Mass Index, BMI）、体质量指数平方、吸烟状态、环境烟草烟雾暴露、饮酒情况、体力活动、高敏C反应蛋白（high-sensitivity C-reactive protein）、血尿酸水平、高血压、心脏病、糖尿病、道路交通与铁路噪声、季节效应及研究区域的影响。 b IL6-174G/C基因多态性与TPM10对HRV的基因型特异性主效应的p值（共显性遗传模型）。 c 针对IL6-174G/C基因多态性对HRV各项指标的主效应，分别检验了加性、显性与隐性遗传模型下的p值；本文呈现了统计学显著性最高的遗传模式对应的p值（1代表加性模型，2代表显性模型）。 d 每1μg/m³的TPM10浓度升高对应的效应。 e 以参考基因型G/G作为对照。