Results comparison for different time limits applied to the Gurobi solver.

Four different time limits were evaluated to test the sensitivity of optimal solutions to the early termination criterion (60 s) imposed. In all cases, the λ-value was fixed to a reference optimum, the one obtained when the time limit was 60 s. Mean values for the 11 contexts (with the standard deviation within round brackets) are shown for the correlation between flux values and data,

ρ
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(V,D), the mean residual,

R
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(V,D), and the cardinality, i.e., number of reactions of the extracted models,

Card.
-

.

为检验最优解对所施加的60秒提前终止准则(early termination criterion)的敏感性，本研究设置四种不同时间限制开展测试。所有实验场景中，λ值均固定为参考最优值——即当时间限制设为60秒时所得到的最优解。本文呈现了11类实验场景下的各项指标均值（标准差以圆括号标注），包括通量值(flux values)与实验数据的相关系数$ar{
ho}(V,D)$、平均残差$ar{R}(V,D)$，以及提取模型的反应总数$oldsymbol{Card.}$（即所包含的反应数目）。