Women First INTER-NDA SAS Datafile in Preconception Maternal Nutrition Trial Women First (Enrollment to 24 Months After Birth)

INTER-NDA 24-Month Assessment Data in the SAS software format. Finalized August 2024.
Study Description
Multi-country three-arm, individually randomized, non-masked, controlled trial to ascertain the benefits of ensuring optimal maternal nutrition before conception and providing an evidence base for programmatic priority directed to minimizing the risk of malnutrition in all females of reproductive age. The objective is to determine the benefits to the offspring of women in poor, food-insecure environments of commencing a daily comprehensive maternal nutrition supplement (with additional balanced calorie/protein supplement for underweight participants) ≥ 3 months prior to conception versus the benefits of commencing the same supplement at 12 weeks gestation and also to compare offspring outcomes with those of a control group which receives no supplement. Women with eligible pregnancies in four low-resource countries (Democratic Republic of Congo, Guatemala, India, and Pakistan)

INTER-NDA 24个月评估数据（SAS软件格式），于2024年8月定稿。
研究描述：
本研究为一项多国三臂、个体随机、非盲对照试验，旨在明确孕前优化孕产妇营养的获益，并为制定以降低全体育龄女性营养不良风险为导向的项目优先级提供循证依据。本研究的核心目标为：对比在贫困、粮食不安全环境中，女性于孕前≥3个月开始每日服用全面孕产妇营养补充剂（体重不足受试者可额外获得均衡热量/蛋白质补充剂），与妊娠12周时开始服用同款补充剂，对其所生育后代的获益差异；同时将上述两组的后代结局与未服用任何补充剂的对照组进行比较。本研究纳入4个低资源国家（刚果民主共和国、危地马拉、印度、巴基斯坦）的符合入组条件的妊娠女性。