GK-1B

GK-1B investigates the impact of Bifidobacterium bifidum treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection.The identification of the sample GK-1B:<br>G: Denotes the strain ST-104 of Clostridioides difficile.<br>K: Represents timepoint 3, indicating sampling after treatment.<br>1: Refers to the specific mouse number under investigation.<br>B: Indicates the treatment administered, which in this case is Bifidobacterium bifidum.

本数据集围绕GK-1B展开研究，旨在探究两歧双歧杆菌（Bifidobacterium bifidum）干预对艰难梭菌（Clostridioides difficile）感染小鼠的肠道菌群的影响。研究人员采集感染后小鼠的粪便样本，采用Invitrogen完成前处理，并在Ion Torrent NGS System上完成测序。通过Ion Reporter SW（16S）分析软件开展的菌群分析结果显示，感染后第1、3、6天的微生物类群动态发生显著变化，该研究为阐明艰难梭菌感染期间益生菌调节肠道菌群的潜在可能性提供了关键依据。
针对样本GK-1B的命名规则说明如下：
G：代表所使用的艰难梭菌菌株ST-104；
K：代表第3个采样时间点，即干预处理后进行采样；
1：代表本次研究的特定小鼠编号；
B：代表本次施加的干预措施，即采用两歧双歧杆菌进行处理。