Time matters: community assembly in the pig fecal microbiome in the first month of life.

Despite the wealth of research into strategies for microbiome modulation in pigs, studies have found mixed results. Here, we follow the development of the pig gut microbial community in a monitoring experiment, sampling the microbiome at a high temporal resolution. We find rapid successional dynamics, as well as non-linear abundance patterns over time for many key taxa in the community. Our research demonstrates the importance of considering time in microbiome modulation strategies.

尽管已有大量关于猪肠道微生物组（microbiome）调控策略的研究，但相关实验结果却并不一致。本研究通过一项监测实验追踪猪肠道微生物群落的演替过程，并以高时间分辨率对其微生物组进行采样。研究发现，该群落展现出快速的演替动态，且其中多数关键类群的丰度随时间呈现非线性变化模式。本研究证实了在制定肠道菌群调控策略时，需将时间因素纳入考量的重要性。