Supplementary materials: Identification of a lncRNA Prognostic Signature-related to Stem Cells index and its Significance in Colorectal Cancer

<b>Figure S1: X-tile plots of
mRNAsi-related lncRNA signature for optimal cut-off determination in the
training cohort. </b>(A-B) The cut-off
(IRS= 0.97) was optimized to separate low mRNAsi-related lncRNA signature
(blue) from high mRNAsi-related lncRNA signature (gray) in the frequency
histogram of the training cohort. (C) Kaplan-Meier curve for testing the
survival of sample subsets defined by the optimized cutoff value of
mRNAsi-related lncRNA signature.<b></b>
<b> </b>
<b>Table
S1. </b>List
of TCGA IDs for randomly grouped training and validation cohort<b></b>
<b> </b>
<b>Table
S2. </b>The
univariate screening of mRNAsi-related lncRNA for overall survival in the
training

<b>Table
S3. </b>The
univariate screening of mRNAsi-related lncRNA for overall survival in the
training cohort

<b>Table
S4.</b> The
univariate analysis of mRNAsi-related lncRNA signature for overall survival
in the training cohort
<b> </b>
<b>Table
S5.</b> The
univariate analysis of mRNAsi-related lncRNA signature for overall survival
in the validation cohort

<b>Table
S6. </b>The
correlation of each of five mRNAsi-related lncRNAs with mRNA from the same patients

<b>Table
S7. </b>The
GO analysis of the mRNAsi-related lncRNA signature

<b>Table
S8. </b>The
KEGG pathway analysis of the mRNAsi-related lncRNA signature

**补充图S1：训练队列中用于确定最佳截断值的mRNA干细胞指数（mRNA stemness index, mRNAsi）相关长链非编码RNA（long non-coding RNA, lncRNA）特征的X-tile图**
(A-B) 在训练队列的频率直方图中，优化得到截断值（IRS= 0.97），以区分低mRNA干细胞指数相关长链非编码RNA特征组（蓝色）与高mRNA干细胞指数相关长链非编码RNA特征组（灰色）。(C) 基于该优化截断值划分的样本亚组的生存分析Kaplan-Meier曲线。

**补充表S1**：随机分组的训练队列与验证队列的癌症基因组图谱（The Cancer Genome Atlas, TCGA）样本ID列表

**补充表S2**：训练队列中针对总生存期的mRNA干细胞指数相关长链非编码RNA单变量筛选

**补充表S3**：训练队列中针对总生存期的mRNA干细胞指数相关长链非编码RNA单变量筛选

**补充表S4**：训练队列中mRNA干细胞指数相关长链非编码RNA特征的总生存期单变量分析

**补充表S5**：验证队列中mRNA干细胞指数相关长链非编码RNA特征的总生存期单变量分析

**补充表S6**：5个mRNA干细胞指数相关长链非编码RNA分别与同样本信使RNA（messenger RNA, mRNA）的相关性分析

**补充表S7**：mRNA干细胞指数相关长链非编码RNA特征的基因本体（Gene Ontology, GO）富集分析

**补充表S8**：mRNA干细胞指数相关长链非编码RNA特征的京都基因与基因组百科全书（Kyoto Encyclopedia of Genes and Genomes, KEGG）通路富集分析