Whole transcriptome sequencing of peripheral blood from opioid use disorder [miRNA-seq]. Whole transcriptome sequencing of peripheral blood from opioid use disorder [miRNA-seq]

7 male OUD patients and 7 male health controls with demographic and clinical data matched were enrolled in this study. rRNA removed library and small RNA library were constructed using peripheral blood RNA. RNA-seq was used to investigate the peripheral transcriptomic changes between the two groups. Overall design: transcriptome profile of 7 male OUD patients and 7 male health controls

本研究纳入人口学与临床数据匹配的7名男性阿片使用障碍（Opioid Use Disorder, OUD）患者及7名男性健康对照者。研究人员采用外周血RNA构建了rRNA去除文库（rRNA removed library）与小RNA文库（small RNA library），并通过RNA测序（RNA-seq）技术探究两组样本的外周血转录组变化。整体实验设计：7名男性阿片使用障碍患者与7名男性健康对照者的转录组谱分析。