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Expression of Splicing Factor Genes is Reduced in Human Obesity and Contributes to Enhanced Lipogenesis

ChEBI2011-08-02 更新2026-07-21 收录

肥胖症分子机制

剪接因子基因表达

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-22435 数据链接链接失效反馈

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Expression of Splicing Factor Genes is Reduced in Human Obesity and Contributes to Enhanced Lipogenesis

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创建时间：

2011-08-02

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肥胖症分子机制

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A subset of obese humans has relatively low plasma levels of leptin. This finding has suggested that in some cases abnormal regulation of the leptin gene in adipose tissue is etiologic in the pathogen

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Pharmacologic IRE1/XBP1s Activation Promotes Systemic Adaptive Remodeling in Obesity. Pharmacologic IRE1/XBP1s Activation Promotes Systemic Adaptive Remodeling in Obesity

肥胖症分子机制

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RNA was isolated from livers of DIO mice treated with IXA4 or vehicle (n=4 per condition) using the Zymo Research Quick-RNA Miniprep Kit according to the manufacturer’s instructions. RNA sequencing wa

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Obesity stimulates the infiltration of adipose tissue by innate immune cells, which in turn promote insulin resistance via the NFkB mediated induction of pro-inflammatory cytokines, which interfere wi

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Expression of Splicing Factor Genes is Reduced in Human Obesity and Contributes to Enhanced Lipogenesis

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