Osteoblast-Endothelial Transition Contributes to Glucocorticoid-Induced Bone Loss. Osteoblast-Endothelial Transition Contributes to Glucocorticoid-Induced Bone Loss

To investigate the transition of osteoblast to endothelial-like cell in glucocorticoid induced osteoporosis. We performed gene expression profiling analysis using data obtained from RNA-seq of dexamethasone treated vs control. Overall design: Comparative gene expression profiling analysis of RNA-seq data for dexamethasone treated vs control with three biological replicates included in each group.

本研究旨在探究糖皮质激素诱导性骨质疏松症中，成骨细胞向类内皮细胞的转化过程。我们采用地塞米松处理组与对照组的RNA测序（RNA-seq）数据开展基因表达谱分析。实验设计概述：针对地塞米松处理组与对照组的RNA测序数据进行对比基因表达谱分析，每组均设置3次生物学重复。