Additional file 3: of Inferring miRNA sponge co-regulation of protein-protein interactions in human breast cancer

Functional enrichment results of hub genes in the BRCA-related miRSCoPPI network. For the experimentally validated miRNA-target interactions, the numbers of enriched GO biological processes and KEGG pathways are 337 and 30, respectively. For the putative computationally predictive miRNA-target interactions, the numbers of enriched GO biological processes and KEGG pathways are 338 and 15, respectively. The p-values are adjusted by Benjamini-Hochberg method. (XLSX 86Â kb)

BRCA相关miRSCoPPI网络中枢纽基因的功能富集分析结果。针对经实验验证的miRNA-靶基因相互作用，富集的基因本体（Gene Ontology, GO）生物过程条目数与京都基因与基因组百科全书（Kyoto Encyclopedia of Genes and Genomes, KEGG）通路条目数分别为337和30；针对经计算预测得到的潜在miRNA-靶基因相互作用，富集的GO生物过程与KEGG通路条目数分别为338和15。所有P值均经Benjamini-Hochberg方法校正。（XLSX格式，文件大小86 KB）