The Transcription factor Zeb2 ia required to maintain tissue-specific identities of macrophages [microarray]. The Transcription factor Zeb2 ia required to maintain tissue-specific identities of macrophages [microarray]

Microarray, Bulk RNA Sequencing and Single cell RNA Sequencing of different murine tissue-resident macrophage populations to assess role of Zeb2 and LXRa Overall design: Microarray = 4 replicates of alveolar Macrophages and 3 of Microglia. These were compared with previously published data (GSE75225, GSE76999 and GSE15907) to identify core macrophage profile. The file normalized_data_allsamples.txt available at the foot of this record contains the normalized values for the new samples included in this series and all re-analyzed samples.

本数据集通过对不同小鼠组织驻留巨噬细胞群体开展微阵列（Microarray）、批量RNA测序（Bulk RNA Sequencing）与单细胞RNA测序（Single cell RNA Sequencing）实验，旨在评估Zeb2与LXRα的功能。整体实验设计如下：微阵列实验包含4份肺泡巨噬细胞重复样本与3份小胶质细胞重复样本。将上述样本与已发表数据集（GSE75225、GSE76999及GSE15907）进行比对，以鉴定核心巨噬细胞表达谱。本记录页面底部提供的normalized_data_allsamples.txt文件，包含本研究系列新增样本及所有重新分析样本的标准化表达量数据。