Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP and synthetic 1,5-(PP)2-IP4 (1,5-IP8)
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Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP and synthetic 1,5-(PP)2-IP4 (1,5-IP8) Descriptor: (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)], ADENOSINE-5'-DIPHOSPHATE, Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2, ... Authors: Wang, H, Shears, S.B. Deposit date: 2014-04-14 Release date: 2014-08-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Synthesis of Densely Phosphorylated Bis-1,5-Diphospho-myo-Inositol Tetrakisphosphate and its Enantiomer by Bidirectional P-Anhydride Formation. Angew.Chem.Int.Ed.Engl., 53, 2014
人类二磷酸肌醇五磷酸激酶2（diphosphoinositol pentakisphosphate kinase 2，PPIP5K2）催化结构域与腺苷-5'-二磷酸（adenosine-5'-diphosphate，ADP）及合成型1,5-(PP)₂-IP4（1,5-IP8）结合的晶体结构。描述内容：(1R,3S,4R,5S,6R)-2,4,5,6-四(膦酰氧基)环己烷-1,3-二基双[三氢(二磷酸酯)]、腺苷-5'-二磷酸、肌醇六磷酸与二磷酸肌醇五磷酸激酶2……作者：Wang, H、Shears, S.B. 存储日期：2014-04-14，发布日期：2014-08-06，最后修改日期：2023-09-20。实验方法：X射线衍射（分辨率1.9埃）。引用文献：《通过双向磷酐键形成法合成高磷酸化双-1,5-二磷酰肌醇四磷酸及其对映异构体》，《Angew.Chem.Int.Ed.Engl.》，53卷，2014年
创建时间：
2014-04-14
