Cancer-Associated Fibroblasts Promote Vasculogenic Mimicry of Colorectal Cancer by Epigenetic Silencing of Decorin [RNA-Seq]

To investigate the transcriptome landscape differences between CAFs and NFs in colorectal cancer, we extracted primary fibroblasts from colorectal cancer tissue and para-cancerous tissue for transcriptome sequencing. Comparative gene expression profiling analysis of RNA-seq data for CAFs and NFs.

为探究结直肠癌中癌症相关成纤维细胞（cancer-associated fibroblasts，CAFs）与正常成纤维细胞（normal fibroblasts，NFs）的转录组图谱差异，我们从结直肠癌组织及癌旁组织中提取原代成纤维细胞进行转录组测序，并对两组样本的RNA测序（RNA-seq）数据开展比较基因表达谱分析。