EffectiveDB

This FAIRsharing record describes: The Effective database contains pre-calculated predictions of bacterial secreted proteins and of functional secretion systems. Effective bundles various tools to recognize Type III secretion signals, conserved binding sites of Type III chaperones, eukaryotic-like domains and subcellular targeting signals in the host. Beyond the analysis of arbitrary protein sequence collections, the new release of Effective also provides a "genome-mode", in which protein sequences from nearly complete genomes or metagenomic bins can be screened for the presence of three important secretion systems (type III, IV, VI).

本FAIRsharing记录条目所描述的Effective数据库，收录了经预计算得到的细菌分泌蛋白及功能分泌系统的预测结果。Effective集成了多款分析工具，可用于识别III型分泌信号（Type III secretion signals）、III型分子伴侣（Type III chaperones）的保守结合位点、真核样结构域（eukaryotic-like domains）以及宿主内的亚细胞靶向信号（subcellular targeting signals）。除支持对任意蛋白质序列集开展分析外，新版Effective还提供了“基因组模式（genome-mode）”，该模式可对近乎完整的基因组或宏基因组分箱（metagenomic bins）对应的蛋白质序列进行筛查，以检测其中是否存在三类重要的分泌系统：III型、IV型及VI型分泌系统。