Respiratory Syncytial Virus-Associated Acute Lower Respiratory Infections in Children With Bronchopulmonary Dysplasia

Background Respiratory syncytial virus (RSV) is among the most important causes of acute lower respiratory tract infection (ALRI) in young children. We assessed the severity of RSV-ALRI in children less than 5 years old with bronchopulmonary dysplasia (BPD). Methods We searched for studies using EMBASE, Global Health, and MEDLINE. We assessed hospitalization risk, intensive care unit (ICU) admission, need for oxygen supplementation and mechanical ventilation, and in-hospital case fatality (hCFR) among children with BPD compared with those without (non-BPD). We compared the (1) length of hospital stay (LOS) and (2) duration of oxygen supplementation and mechanical ventilation between the groups. This dataset contains the full extraction records of the literature review.

背景 呼吸道合胞病毒（Respiratory syncytial virus, RSV）是引发幼儿急性下呼吸道感染（acute lower respiratory tract infection, ALRI）的最主要病因之一。本研究针对5岁以下合并支气管肺发育不良（bronchopulmonary dysplasia, BPD）的儿童，评估其RSV相关急性下呼吸道感染的严重程度。
方法 我们通过EMBASE、Global Health及MEDLINE数据库检索相关研究，对比合并BPD与未合并BPD（非BPD组）儿童的住院风险、重症监护病房（intensive care unit, ICU）收治率、氧疗需求、机械通气需求以及住院期间病死率（in-hospital case fatality, hCFR）；同时比较两组的（1）住院时长（length of hospital stay, LOS）与（2）氧疗及机械通气持续时间。
本数据集包含本次文献综述的全部提取记录。