Binary Depletion matrices
收藏DataCite Commons2020-12-01 更新2024-07-28 收录
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https://figshare.com/articles/dataset/Binary_Depletion_matrices/13253810
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Binary depletion matrices at 5% FDR. For the Sanger and Broad individual (uncorrected datasets) processed with CRISPRcleanR (CCR), CRISPRcleanR+JACKS (CCRJ) and CERES. The Binary depletion matrices for the integrated datasets under the three pre-processing methods above with four different batch correction pipelines:1. ComBat only2. ComBat+Quantile normalisation (QN)3. ComBat+ QN + PC1 (first principal component removed)4. ComBat+QN+PC1-2 (first two principal components removed)
5%错误发现率(FDR)下的二元缺失矩阵。针对桑格(Sanger)与布罗德(Broad)的单组未校正数据集,分别经CRISPRcleanR(CCR)、CRISPRcleanR+JACKS(CCRJ)及CERES三种方法预处理。上述三种预处理方法下的整合数据集对应的二元缺失矩阵,搭配四种不同的批次校正流程:1. 仅ComBat校正;2. ComBat结合分位数归一化(QN);3. ComBat+分位数归一化+去除第一主成分(PC1);4. ComBat+分位数归一化+去除前两个主成分(PC1-2)
提供机构:
figshare
创建时间:
2020-12-01



