A, B, Body weights of male (A) and female (B) Qrfp-/- mice (red lines) under ad lib feeding of normal chow compared with wild type littermates (blue lines) plotted over time. C, D, Body weights of mal
The ability to generate defined null mutations in mice revolutionized the analysis of gene function in mammals. However, gene-deficient mice generated by using 129-derived embryonic stem (ES) cells ma
Total RNA samples from Vax2 knockout mouse eyes (at least two biological replicates) were profiled by gene expression. As control we used total RNA from wild type eyes. The analysis was carried out