Data for: The impact of wildlife and environmental factors on hantavirus infection in host and its translation into human risk

Identifying factors that drive infection dynamics in reservoir host populations is essential in understanding human risk from wildlife-originated zoonoses. We studied zoonotic Puumala orthohantavirus (PUUV) in the host, the bank vole (Myodes glareolus), populations in relation to the host population, rodent and predator community and environment-related factors and whether these processes are translated into human infection incidence. We used 5-year rodent trapping and bank vole PUUV serology data collected from 30 sites located in 24 municipalities in Finland. We found that PUUV seroprevalence was negatively associated with the abundance of red foxes, but this process did not translate into human disease incidence, which showed no association with PUUV seroprevalence. The abundance of weasels, the proportion of juvenile bank voles in the host populations and rodent species diversity were negatively associated with the abundance index of PUUV-positive bank voles, which, in turn, showed ..., Bank voles and other rodents (all together eight rodent species) were trapped at 30 study sites located in 24 municipalities across the Southern half of Finland. The study sites were located along a route across the south part of Finland with circa 30 km intervals. At each site, in total 150 snap traps were set with circa 10 meters intervals along 2–4 transects, which were located in forests and on the border between forests and agricultural fields. The trappings were carried out during September – October from 2001 to 2005. In 2001, 2002, 2004 and 2005, trappings were carried out for two continuous days (traps were set on day 1, checked and reset on day 2 and checked and removed on day 3). In 2003, the trappings were only performed at every second trapping site, lasting for only one day. All captured small mammals were frozen in dry ice in the field and later stored at -20 °C until further processing. The captured bank voles were thawed and dissected. Organ and tissue samples were take...,

明确驱动储存宿主种群感染动态的影响因素，是解析野生动物源性人畜共患病对人类健康风险的核心前提。本研究以宿主棕背䶄（Myodes glareolus）种群为研究对象，针对其携带的人畜共患普马拉正汉坦病毒（Puumala orthohantavirus, PUUV），结合宿主种群特征、啮齿类与捕食者群落结构及环境相关因素展开分析，并探究上述关联是否会转化为人类感染发病案例。本研究使用了芬兰24个市县的30个采样点收集的5年啮齿类捕获数据及棕背䶄PUUV血清学检测数据。研究结果显示，PUUV血清阳性率与赤狐种群丰度呈负相关，但该关联并未转化为人类发病风险——人类发病案例与PUUV血清阳性率无显著关联。鼬类种群丰度、宿主种群中幼年棕背䶄占比及啮齿类物种多样性，与PUUV阳性棕背䶄的丰度指数呈负相关，而该丰度指数又进一步……。研究团队在芬兰南部24个市县的30个采样点开展捕获工作，共捕获棕背䶄及其他啮齿类（总计8个啮齿类物种）。采样点沿芬兰南部的一条路线布设，间距约30公里。每个采样点沿2~4条样线布设共计150个铗捕式陷阱，样线间距约10米，样线设置于森林及森林与农田的交界地带。捕获工作于2001年至2005年的9~10月开展。2001、2002、2004及2005年的捕获工作持续2天：第1日布设陷阱，第2日检查并重置陷阱，第3日检查并移除陷阱。2003年仅在半数采样点开展捕获工作，且仅持续1天。所有捕获的小型哺乳动物均在野外以干冰冷冻保存，后续置于-20℃环境中储存以待进一步实验处理。对捕获的棕背䶄进行解冻与解剖，采集器官及组织样本……