Single-nucleus transcriptomic analysis of the dorsal striatum from 6-month-old G2019S LRRK2 mutant mice

This Zenodo deposit contains a publicly available description of the Dataset: Title: "Single-nucleus transcriptomic analysis of the dorsal striatum from 6-month-old G2019S LRRK2 mutant mice". Description: We performed single-nucleus transcriptomic analysis of the dorsal striatum from 5 wild-type and 5 G2019S LRRK2 mutant mice. This dataset contains the raw fastqs files (grouped together by indexes) from mouse dorsal striatum, sorted by 10 samples (S1 to S10), with files separated by read 1 (R1), read 2 (R2), index reads (I1 and I2), and which lane they were in on the S4 flow cell (L1 to L4). These files are created by bcl2fastq of Cell Ranger; the sequences in those files were used for the alignments. This dataset is made available to researchers via the ASAP CRN Cloud: cloud.parkinsonsroadmap.org. Instructions for how to request access can be found in the User Manual. This research was funded by the Aligning Science Across Parkinson's Collaborative Research Network (ASAP CRN), through the Michael J. Fox Foundation for Parkinson's Research (MJFF). This Zenodo deposit was created by the ASAP CRN Cloud staff on behalf of the dataset authors. It provides a citable reference for a CRN Cloud Dataset本Zenodo存档包含下述公开可用数据集的说明： 数据集标题：《6月龄G2019S突变LRRK2基因小鼠背侧纹状体单细胞核转录组分析》 本研究对5只野生型小鼠与5只G2019S突变LRRK2基因小鼠的背侧纹状体（dorsal striatum）开展单细胞核转录组分析（single-nucleus transcriptomic analysis）。本数据集包含小鼠背侧纹状体的原始FASTQ格式文件（按索引分组），共计10个样本（S1至S10）；文件按Read 1（R1）、Read 2（R2）、索引读取序列（index reads，I1与I2）以及S4测序流槽的测序泳道（L1至L4）进行分类。此类文件由Cell Ranger配套的bcl2fastq工具生成，其中的序列用于后续序列比对分析。 本数据集通过ASAP CRN云平台（cloud.parkinsonsroadmap.org）向研究人员开放。访问申请的操作说明可参阅用户手册。 本研究由Aligning Science Across Parkinson's 协作研究网络（ASAP CRN）通过迈克尔·J·福克斯帕金森症研究基金会（MJFF）资助。 本Zenodo存档由ASAP CRN云平台工作人员代表数据集作者创建，可为CRN云数据集提供可引用的学术参考文献。