Correlation between the number of plasma cells and clinical improvement in retrospective (n = 30, left panels) and prospective (n = 40, right panels) studies.

(A) Strong negative correlation in both studies between the absolute number of IVIg-mobilized plasma cells (PCs) and time to improve one GBS disability-grade. Correlation was analyzed using Spearman test. (B) Day 7 plasmacytosis correlates with faster clinical improvement. Kaplan-Meier analysis of time to one disability-grade improvement following IVIg in relation to day 7 plasma cell counts enumerated on a routine hematology analyzer and confirmed by blood smear exam.

(A) 两项研究均显示，静脉注射免疫球蛋白（Intravenous Immunoglobulin，IVIg）动员的浆细胞（plasma cells，PCs）绝对计数，与吉兰-巴雷综合征（Guillain-Barré Syndrome，GBS）残疾等级改善1级所需时间呈显著负相关。相关性分析采用斯皮尔曼检验（Spearman test）。
(B) 第7天的浆细胞增多与临床改善速度更快相关。本研究针对IVIg治疗后残疾等级改善1级所需时间开展Kaplan-Meier分析（Kaplan-Meier analysis），所纳入分析的第7天浆细胞计数通过常规血液分析仪检测，并经血涂片检查确认。