Data.

Objective
Acute kidney injury (AKI) is one of the common complications after hip fracture in the elderly, and its hospitalization rate, mortality rate and medical expenses are high, resulting in serious social and economic burden. Therefore, we aim to systematically evaluate the incidence and risk factors of postoperative AKI in elderly patients with hip fracture, so as to identify the occurrence of postoperative AKI in elderly patients with hip fracture early, so as to prevent it in advance.
Methods
This meta-analysis adhered to PRISMA guidelines and was registered in PROSPERO (CRD42024498009).We systematically searched Embase, Pubmed, web of science, the cochrane Library, CBM, VIP, CNKI, and Wanfang Data to collect studies on the incidence or influencing factors of postoperative acute kidney injury in elderly patients with hip fracture published up to 18 December 2023. All studies were screened, relevant data extracted, and quality assessed by two independent authors, and meta-analysis was performed using Stata 15.0 software.
Results
A total of 22 articles were included, with a total sample size of 25195 cases and 16 influencing factors. The results of meta-analysis showed that the incidence of postoperative AKI in elderly patients with hip fracture was 17.2% [95%CI (14.3% ~ 20%), P < 0.0001], and there were 6 statistically significant influencing factors, which were baseline serum potassium [OR(95%CI)=2.23 (1.22, 4.05)], hypertension [OR(95%CI)=3.00 (1.75, 5.88)], and chronic kidney disease [OR(95%CI)=4.40 (1.10, 14.75)], diabetes mellitus [OR (95% CI) = 1.84 (1.19, 2.83)], intraoperative hypotension [OR (95% CI) = 5.61 (3.36, 9.35)], and operative time [OR (95% CI) = 1.01 (1.00, 1.02)].
Conclusions
Our study indicated that the incidence of postoperative AKI in elderly patients with hip fracture was 17.2%. Baseline serum potassium, hypertension, chronic kidney disease, diabetes, operative hypotension and operation time were the influencing factors of postoperative AKI in elderly patients with hip fracture.
PROSPERO registration number for this study: CRD42024498009

## 研究目的
急性肾损伤（Acute kidney injury, AKI）是老年髋部骨折术后常见并发症之一，其住院率、死亡率及医疗费用均居高不下，造成了严重的社会经济负担。本研究旨在系统评价老年髋部骨折患者术后急性肾损伤的发生率及危险因素，以期早期识别该类患者术后AKI的发生风险，进而实现提前干预预防。

## 研究方法
本荟萃分析严格遵循PRISMA指南规范，并已在PROSPERO平台完成注册（注册号：CRD42024498009）。研究系统检索了Embase、PubMed、Web of Science、Cochrane图书馆、中国生物医学文献数据库（CBM）、维普资讯（VIP）、中国知网（CNKI）及万方数据，收集截至2023年12月18日发表的、关于老年髋部骨折患者术后急性肾损伤发生率或影响因素的相关研究。由2名独立研究者分别完成文献筛选、数据提取及质量评价，并采用Stata 15.0软件进行荟萃分析。

## 研究结果
本研究共纳入22篇文献，总样本量达25195例，涉及16个潜在危险因素。荟萃分析结果显示：老年髋部骨折患者术后AKI发生率为17.2%[95%CI(14.3%~20%)，P<0.0001]；其中6个危险因素具有统计学意义，分别为基线血清钾[OR(95%CI)=2.23(1.22, 4.05)]、高血压[OR(95%CI)=3.00(1.75, 5.88)]、慢性肾脏病[OR(95%CI)=4.40(1.10, 14.75)]、糖尿病[OR(95%CI)=1.84(1.19, 2.83)]、术中低血压[OR(95%CI)=5.61(3.36, 9.35)]及手术时长[OR(95%CI)=1.01(1.00, 1.02)]。

## 研究结论
本研究结果表明，老年髋部骨折患者术后AKI发生率为17.2%；基线血清钾水平、高血压、慢性肾脏病、糖尿病、术中低血压及手术时长均为该类患者术后AKI的影响因素。

本研究PROSPERO注册号：CRD42024498009