Functional Ultrasound Imaging (fUSI) data from head-fixed, freely running mice

This dataset contains whole-brain functional Ultrasound Imaging (fUSI) recordings and associated behavioral/physiological signals collected in head-fixed , freely running mice, under conditions of spontaneous behaviour.The files are processed data, including Power Doppler data for all acquisitions performed for the following study: A Landemard, M Krumin, KD Harris, and M Carandini, "Brainwide blood volume reflects opposing neural populations", <i>bioRxiv</i> 2025 (<i>Nature</i>, 2026).The repository is in the BIDS format, organized as follows:fUSI power-Doppler runs: sub-*/fusi/*_pwd.nii.gz with JSON sidecars.Whisker activity (when available): sub-*/fusi/*_recording-whisking_physio.tsv.gz,Eye position (when available): sub-*/fusi/*_recording-eye_physio.tsv.gz,Running wheel signals (when available) sub-*/fusi/*_recording-wheel_physio.tsv.gz (+ JSON sidecars).One angiography scan per subject: sub-*/angio/*_pwd.nii.gz (+ JSON sidecars).Per-subject acquisition tables: sub-*/sub-*_scans.tsv.Atlas alignment and processed derivatives.The code to analyze these files is available on GitHub, at https://github.com/agneslandemard/fusi_analyses

本数据集包含头部固定、自由活动小鼠在自发行为状态下采集的全脑功能超声成像（functional Ultrasound Imaging, fUSI）记录，以及配套的行为与生理信号。所有文件均为处理后的数据，涵盖下述研究的全部采集任务的功率多普勒数据：A Landemard、M Krumin、KD Harris与M Carandini于2025年在预印本平台bioRxiv发布、2026年正式发表于《Nature》的论文《全脑血容量反映拮抗神经群体》（Brainwide blood volume reflects opposing neural populations）。该数据集采用脑成像数据结构（Brain Imaging Data Structure, BIDS）组织，具体结构如下：fUSI功率多普勒序列：存储于sub-*/fusi/路径下，文件格式为*_pwd.nii.gz，附带JSON附属文件；胡须活动数据（若可用）：sub-*/fusi/路径下的*_recording-whisking_physio.tsv.gz；眼部位置数据（若可用）：sub-*/fusi/路径下的*_recording-eye_physio.tsv.gz；转轮运动信号数据（若可用）：sub-*/fusi/路径下的*_recording-wheel_physio.tsv.gz（附带JSON附属文件）；每名受试者的血管造影扫描数据：sub-*/angio/路径下的*_pwd.nii.gz（附带JSON附属文件）；单受试者采集记录表：sub-*/sub-*_scans.tsv；脑图谱配准与处理后的衍生数据集。用于分析上述文件的代码已托管于GitHub，仓库地址为https://github.com/agneslandemard/fusi_analyses