Targeting Myc signaling pathway by inhibition of histone demethylase JMJD2B

ChEBI2014-01-01 更新2026-07-21 收录

癌症表观遗传学

靶向药物开发

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-45970 数据链接链接失效反馈

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Targeting Myc signaling pathway by inhibition of histone demethylase JMJD2B

创建时间：

2014-01-01

Genome-wide maps of H3K27ac and H3K4me1 in primary normal fibroblasts and matched cancer-associated fibroblasts

癌症表观遗传学

成纤维细胞活化

To understand the driving mechanisms for CAF activation, we performed H3K27ac and H3K4me1 Cleavage Under Targets and Tagmentation (CUT&Tag) analysis in six pairs of NFs and CAFs. At H3K4me1+ sites, we

NIAID Data Ecosystem70

Epigenomic study identifies a novel mesenchyme homeobox2-GLI1 transcription axis involved in cancer drug resistance, overall survival and therapy prognosis in lung cancer patients

癌症表观遗传学

药物耐药性

Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic

DataONE2020-06-24 更新60

Mapping Context-Aware Phosphosite Regulation of Protein–Protein Interactions Using Deep Learning and Pan-Cancer Proteomics

磷酸化位点调控蛋白互作预测

癌症表观遗传学

Phosphorylation dynamically orchestrates the protein–protein interaction (PPI) network that governs cellular signaling, and its dysregulation frequently drives malignant transformation and neurodegene

NIAID Data Ecosystem30

Global 5mC and 5hmC levels in sixteen pairs of HCC and non-HCC samples and two HCC cell lines investigated by UPLC-MS/MS

癌症表观遗传学

甲基化测序

We performed UPLC-MS/MS to investigate global 5mC and 5hmC levels in sixteen pairs of HCC and non-HCC samples and two HCC cell lines (97L and LM6 cells). We found that 5mC and 5hmC were frequently dec

Figshare2016-01-19 更新70

Summary of OPCML methylation in cell lines and primary tumors.

癌症表观遗传学

DNA甲基化分析

Summary of OPCML methylation in cell lines and primary tumors.

NIAID Data Ecosystem30