Human immunodeficiency virus 1 Genome sequencing. Human immunodeficiency virus 1

Samples from HIV-infected pregnant women from a rural area in southern Mozambique were analysed. Only women with HIV-1 RNA >400c/mL at delivery were included in the analysis. HIVDRM were determined using MiSeq® (detection threshold 1%) at the first antenatal care (ANC) visit and at the time of delivery.

本研究分析了来自莫桑比克南部农村地区的人类免疫缺陷病毒（HIV，Human Immunodeficiency Virus）感染孕妇样本。本分析仅纳入分娩时HIV-1核糖核酸（RNA）水平＞400拷贝/毫升的女性。研究分别在首次产前检查（ANC，Antenatal Care）及分娩时，采用MiSeq®平台（检测阈值为1%）对HIV耐药突变（HIVDRM, HIV Drug Resistance Mutation）进行检测。