Differential mRNA expression analysis of H460 cells and A549 cells after trametinib treatment

MAP kinse-ERK kinase inhibitor (MEKi) resistance remains unknown. We determined gene expression profiling in MEKi-resistant cells and MEKi-sensitive cells after MEKi treatment using RNA-seq analysis Overall design: Transcription profiling of lung cancer cells

丝裂原活化蛋白激酶-细胞外调节蛋白激酶抑制剂（MAP kinase-ERK kinase inhibitor，MEKi）的耐药性仍未明确。本研究采用RNA测序（RNA-seq）分析方法，对经MEKi处理后的MEKi耐药细胞与MEKi敏感细胞开展了基因表达谱分析。实验总体设计：肺癌细胞的转录谱分析。